1-Boc-3-piperidone CAS 98977-36-7

Taipitopito Hua

Whakaahuatanga Haumaru	24/25 – Kaua e pa ki te kiri me nga kanohi.
WGK Tiamana	3
Waehere HS	29339900
Te akomanga morearea	MAOKE

Kupu Whakataki	Ko te n-tert-butoxycarbonyl-3-piperidone he pesticide nui, he takawaenga hoki mo nga takawaenga rongoa me etahi atu taapiri matū. He maha nga momo tikanga waihanga:(1) te whakamahi i te γ-butyrolactone hei rauemi mata, i muri i te benzylaminolysis, hydrolysis, esterification, condensation ki te ethyl bromoacetate, cyclization, te tauhohenga ono-taahiraa o te hydrolytic decarboxylation hua 1-benzyl-3-piperidone hydrochloride, whai muri i te debenzylation o te roopu tert-butoxycarbonyl ki te hoatu n-tert-butoxycarbonyl-3-piperidone (US0053565). (2) me te 3-hydroxypyridine hei rauemi mata, te tauhohenga me te benzyl bromide ki te whakaputa i te tote haukinia quaternary, te whakaiti konutai borohydride, Palladium carbon debenzyl i runga i te tert-butoxycarbonyl, N-tert-butoxycarbonyl-3-piperidone (CN103204801) te whakamahana o te dimethyl sulfoxide.
Taupānga	Ko te n-tert-butoxycarbonyl-3-piperidone he takawaenga i roto i te whakahiato waro me te takawaenga i roto i te rongoa, ka taea te whakamahi i roto i te rangahau taiwhanga me te tukanga whakawhanaketanga me te tukanga whakahiato rongoa matū, te nuinga e whakamahia ana mo te whakahiatotanga mana stereo o nga pūhui chiral.
Whakamahi	Ko te N-tert-butoxycarbonyl-3-piperidone e whakamahia ana mo te whakahiatotanga o nga pūhui chiral.