1H-Pyrazole-3-carboxylicacid 5-methyl-(CAS # 696-22-0)
| Nga Tohu Whakamate | Xi – Irritant |
| Waehere Morearea | R36/37/38 – He whakapataritari ki nga kanohi, te punaha manawa me te kiri. |
| Whakaahuatanga Haumaru | S26 – Mena ka pa ki nga kanohi, horoi tonu ki te nui o te wai me te rapu tohutohu hauora. S37/39 – Kia mau nga karapu tika me te whakamarumaru kanohi/kanohi |
Kupu Whakataki
He pūhui waro me te tātai matū C5H5N2O2. Ko te tikanga he totoka kowhai kowhai ki te kowhai kowhai.
E rua nga roopu mahi o te puhui, he mowhiti pyrazole tetahi, he roopu mahi waikawa carboxylic tetahi. He ngawari te wairewa, he wairewa ki te wai me nga whakarewa pararopi noa. Ko te roopu methyl i roto i tona hanganga ka hanga i te hydrophobic.
Hei pūhui heterocyclic, 5-methyl-he momo mahi koiora. Ka whakamahia nuitia i roto i te rangahau rongoa me te whakahiato raau taero, he maha nga wa hei rauemi mata, hei takawaenga ranei. Ko nga tono motuhake ko te whakahiatotanga o te huaora B1 tairitenga, te ngarara, te aukati plavix (he puhui e whakamahia ana hei aukati i te tipu tipu), me nga mea pera.
Whakaritenga, 5-mewaro-ka taea te whiwhi ma te tauhohe i te ngota hauota o te mowhiti pyrazole me te kaihoko methylating (hei tauira methyl iodide). Ka mahia tenei tikanga e te tauhohenga N-methylation, ko te tikanga noa ko te tauhohenga o te nucleophile e rite ana me te reagent N-methyl.
