2 4-Dichloro-5-methylpyrimidine（CAS# 1780-31-0)
Morearea me te Haumaru
| Nga Tohu Whakamate | C – Huka |
| Waehere Morearea | 34 – He weranga |
| Whakaahuatanga Haumaru | S26 – Mena ka pa ki nga kanohi, horoi tonu ki te nui o te wai me te rapu tohutohu hauora. S36/37/39 – Mau kakahu whakamarumaru tika, karapu me te whakamarumaru kanohi/kanohi. S45 – Ki te puta he aitua, ki te kore ranei koe e pai, rapu wawe i nga tohutohu hauora (whakaatuhia te tapanga ina taea.) S27 – Wewetehia nga kakahu poke katoa. |
| UN ID | UN 3261 8/PG 2 |
| WGK Tiamana | 3 |
| TSCA | Ae |
| Waehere HS | 29335990 |
| Te akomanga morearea | 8 |
| Roopu Tarapi | III |
2 4-Dichloro-5-methylpyrimidine（CAS# 1780-31-0) Nga korero
| Whakamahi | 2, 4-dichloro-5-methylpyrimidine ka taea te whakamahi ki te whakarite i te 2-fluoro-5-trifluoromethylpyrimidine. Ko te 2-fluoro-5-trifluoromethylpyrimidine he takawaenga nui mo te whakahiato o nga rongoa, ka taea te whakamahi ki te whakahiato i nga pūhui dihydrofuran mowhiti, a ka taea te whakamahi i nga pūhui dihydrofuran mowhiti hei whakakapi GPR119, mo te maimoatanga o te mate huka, te nui me te mate dyslipidemia. I tua atu, ka taea hoki te whakamahi 2-fluoro-5-trifluoromethylpyrimidine hei takawaenga i roto i te whakahiato o nga raau taero mo te maimoatanga o te mate a Alzheimer me te schizophrenia. |
| whakarite | 5-methyluracil 75g(0.59mol), ūkuikui oxychloride 236g, triethylamine hydrochloride 16.5g(0.12mol), tāpiri ki te ipu tauhohenga, whakamahana ki te 100 ℃ ~ 110 ℃, Reflux tauhohenga 5H, mātao ki te 40 ℃ 8(maota ūkuikui penta40 ℃ 1.19mol), tauhohenga tiaki wera 2H. I muri i te otinga o te tauhohenga, i whakahokia mai te phosphorus oxychloride i te whakamarumaru i raro i te pehanga iti, a ka haere tonu te whakamarumaru i raro i te pehanga iti kia whiwhi 88g(0.54mol) o 2, 4-dichloro-5-methylpyrimidine i roto i te hua o te 91.5%. |
Tuhia to korero ki konei ka tukuna mai ki a matou
