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2,4,5-Trifluorophenylacetic Waikawa (CAS # 209995-38-0)

Āhuatanga matū:

Tātai rāpoi C8H5F3O2

Molar Mass 190.12

Kiato 1.468±0.06 g/cm3(Whakaahua)

Ira Whakarewa 121-125 °C

Ira Pounamu 255.0±35.0 °C(I Matapaetia)

Irahiko 108°C

Waiwaihanga Chloroform (Paku), DMSO (Paku), Methanol (Paku)

Te Kohu Kohu 0.00866mmHg i te 25°C


Taipitopito Hua

Tohu Hua

Taupānga

Ko te waikawa 2,4, 5-trifluorophenylacetic he totoka ma e whakamahia ana ki te whakahiato i nga takawaenga sitagliptin tarukino hou mo te maimoatanga o te mate huka momo II. Ko te sitagliptin te kai aukati DPP-IV tuatahi i whakaingoatia e Merck. He pai te rongoa, he iti nga paanga o te taha, he pai te haumaru me te manawanui i roto i te maimoatanga o te mate huka momo II, me te whanui o te maakete.

Whakatakotoranga

Te Tioataata Te ahua
Tae Ma ki Off-White
pKa 3.78±0.10(Te Matapae)
Te Tikanga Rokiroki Kua hiri ki te maroke, Te Pawera o te rūma
Taupū Refactive 1.488

Haumaru

Nga Tohu Moorearea Xi - Irirangi
Whakariri
Waehere Whakararuraru R37/38 - Ka whakapataritari ki te punaha manawa me te kiri.
R41 - He kino kino ki nga kanohi
Whakaahuatanga Haumaru S26 - Mena ka pa ki nga kanohi, horoi tonu ki te nui o te wai me te rapu tohutohu hauora.
S39 - Mau whakamarumaru kanohi / kanohi.
WGK Tiamana 3
Waehere HS 29163990
Ko te Roopu Whakamate

Te Tarapi me te Rokiroki

Kikī i roto i te 25kg/50kg pahu. Puritia ki te wahi pouri, Hiri ki te maroke, Te Pawera Rua

Kupu Whakataki

Te whakauru i te 2,4,5-Trifluorophenylacetic Acid, he totoka ma e whakamahia whanuitia ana i roto i te umanga rongoa mo te whakahiato i nga takawaenga sitagliptin mo te maimoatanga o te mate huka momo II.

Ko te 2,4,5-Trifluorophenylacetic Acid he mea nui ki te hanga o te sitagliptin ki te whakawhanaketanga o tenei rongoa tino whai hua. Ko te Sitagliptin te aukati DPP-IV hou kua tohua e Merck. He pai nga hua whakaora, he iti noa nga paanga taha, te haumaru me te manawanui, a kua waiho hei rongoa mo te maimoatanga o te mate huka momo II.

Ko tetahi o nga painga nui o te 2,4,5-Trifluorophenylacetic Acid ko te mea ka taea e ia te hanga sitagliptin i te utu iti, e taea ai e te hunga takitahi te uru atu ki tenei rongoa whakarereke ora. I tua atu, he tino whai hua ki te maimoatanga o te mate huka me te whakarato tumanako hou mo te hunga e raru ana ki te mate.

Ko te ahua o te 2,4,5-Trifluorophenylacetic Acid he kirikiri ma ki te paura ma, he maamaa ki te tautuhi, ki te hapai, ki te kawe. He ahua pumau ano i raro i nga ahuatanga noa, ko te tikanga ka taea te rongoa mo nga wa roa kaore e paheke.

Ko te 2,4,5-Trifluorophenylacetic Acid he tino pai, ka taea te whakamahi i roto i te whakahiato o etahi atu puhui matatini i tua atu o nga takawaenga sitagliptin. He maha nga tono ahumahi, tae atu ki te hanga o nga matū ahuwhenua, kapia, me nga takawaenga. Ka taea hoki te whakamahi hei rauemi timatanga mo te whakahiatotanga o nga momo momo ngota me nga tono rereke.

I ta maatau kamupene, e whakahihi ana matou ki te tuku 2,4,5-Trifluorophenylacetic Acid ki o taatau kaihoko. Ka tutuki a maatau hua ki nga paerewa kounga teitei rawa atu ka hangaia i runga i nga aratohu tino tika hei whakarite i te rite me te ma.

Hei whakamutunga, ko te 2,4,5-Trifluorophenylacetic Acid he puhui tino whai hua kua waiho hei waahanga nui mo te hanga o te sitagliptin, he rongoa tuatahi mo te mate huka momo II. Ko tana whaihua me te whai hua ka waiho hei taonga nui i roto i nga umanga rongoa me nga umanga matū, a kei te whakapehapeha matou ki te tuku i te 2,4,5-Trifluorophenylacetic Acid ki o taatau kaihoko.


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