5-Bromo-3-nitro-2-pyridinol（CAS# 15862-34-7)
Morearea me te Haumaru
| Waehere Morearea | R22 – He kino ki te horomia R37/38 – He whakapataritari ki te punaha manawa me te kiri. R41 – He kino kino ki nga kanohi R36/37/38 – He whakapataritari ki nga kanohi, te punaha manawa me te kiri. R20 – He kino ma te whakangohanga |
| Whakaahuatanga Haumaru | S26 – Mena ka pa ki nga kanohi, horoi tonu ki te nui o te wai me te rapu tohutohu hauora. S36/37/39 – Mau kakahu whakamarumaru tika, karapu me te whakamarumaru kanohi/kanohi. S36 – Mau kakahu whakamarumaru tika. |
| UN ID | 2811 |
| WGK Tiamana | 3 |
| Waehere HS | 29337900 |
| Tuhipoka morearea | He kino |
| Te akomanga morearea | TANGATA |
Nga korero tohutoro
| Whakamahi | Ko te 5-bromo-2-hydroxy-3-nitropyridine he takawaenga pararopi ka taea te whakamahi hei whakarite i nga pūhui 3-amino-1-(2-oxo-2-(3 '-(trifluoromethyl)-[1,1'-biphenyl ]-4-yl) ethyl)-5-(pyrrole alkyl-1-yl-sulfonyl) pyridin-2 (1H) -one, he pūhui aukati DOCK1 tenei pūhui. |
| tikanga whakahiato | Ko te waikawa nitric (60-61%,3.5mL) i tapirihia ki te otinga (10mL) o te 5-bromopyridine -2(1H)-kotahi (1.75g,10.1mmol) i roto i te waikawa pungatara i te 0 ℃. Ka tukuna te ranunga ki te whakamahana ki te pāmahana rūma me te whakaoho mo te 3 haora. Ka ringihia te ranunga tauhohenga ki te wai hukapapa, ka kohia te rerenga o te rerenga ma te tātari. Ko te hua ka horoia ki te wai ka whakamarokehia i roto i te korehau, ka hoatu he 5-bromo-2-hydroxy-3-nitropyridine (960mg,43% te hua) hei totoka ma. 1H NMR(500MHz,CDCl3)δ:8.57(s,1H),8.26(s,1H). |
Tuhia to korero ki konei ka tukuna mai ki a matou
