Boc-L-aspartic acid 1-benzyl ester（CAS# 30925-18-9)
| Whakaahuatanga Haumaru | 24/25 – Kaua e pa ki te kiri me nga kanohi. |
| WGK Tiamana | 3 |
| Waehere HS | 29242990 |
Kupu Whakataki
Ko te Boc-Asp-OBzl(Boc-Asp-OBzl) he pūhui e whai ake nei:
1. Te ahua: Ma te kirikiri toka.
2. tātai rāpoi ngota: C24H27N3O7.
3. Taumaha rāpoi: 469.49g/mol.
4. Ira whakarewa: mo te 130-134 ° C.
Ko te Boc-Asp-OBzl e whakamahia nuitia ana i roto i te matū koiora me te matū pararopi waihanga, he maha nga wa e whakamahia ana i roto i te whakahiatotanga o nga peptides, nga pūmua me nga raau taero, me nga whakamahinga e whai ake nei:
1. Te whakahiato peptide: Hei waahanga o te roopu tiaki (Boc protecting group), ka taea te tiaki i te roopu amino i roto i te waikawa amino waikawa aspartic.
2. Te rangahau tarukino: mo te whakahiato o nga raau taero peptide me te mahi anti-inflammatory, anti-tumor me te mahi ture aukati.
3. Te tauhohenga Enzyme: Ka taea te whakamahi i te Boc-Asp-OBzl mo te taputapu tauhohenga whakakanohi.
Ko te tikanga mo te whakarite i te Boc-Asp-OBzl e whai ake nei:
Ko te waikawa aspartic me te benzoyl chloride ka whakakorikori hei hanga i te tert-butoxycarbonyl-aspartic acid benzyl ester (Boc-Asp-OMe), ka tauhohehia ki te konutai hexoxide ki te whiwhi i te takawaenga ki te ahua o te N-hexanoate. Ka mutu, ka tukuna he tauhohenga benzoylation ki te whakaputa Boc-Asp-OBzl.
Kia tupato ki nga korero haumaru e whai ake nei ina whakamahi ana i te Boc-Asp-OBzl:
1. Ko te puhui ka pa mai te riri me te mate mate ki te tinana o te tangata, me karohia te whakapiri tika ki te kiri me nga kanohi.
2. Me whai tikanga whakamarumaru whaiaro e tika ana i te wa e mahi ana, penei i te mau karapu me nga karaehe.
3. Kia maroke me te hiri i te wa e rokiroki ana, kia matara atu i te ahi me te hāora.
4. A, no te whakamahi me te whakahaere i te Boc-Asp-OBzl, me whai i nga tikanga whakahaere taiwhanga tika me te mahi haumaru.
Kia mahara mai i te wa e whakamahi ana koe i te Boc-Asp-OBzl me etahi atu matū, me tino whai koe i nga aratohu mahi haumaru e pa ana, me te whakahaere i te whakamarumaru whaiaro me te aromatawai morearea kia rite ki te ahuatanga.
