Boc-L-Glutamic acid 1-benzyl ester（CAS# 30924-93-7)

Kupu Whakataki

Ko te waikawa Boc-L-Glutamic 1-benzyl ester(Boc-L-Glutamic acid 1-benzyl ester) he puhui pararopi me te tauira matū o C17H19NO6 me te papatipu ngota o te 337.34. He totoka ma, he wairewa i roto i nga whakarewa waro penei i te waihano, te dimethylformamide me te chloroform.

Ko te waikawa Boc-L-Glutamic 1-benzyl ester e whakamahia ana i roto i te whakahiatotanga o nga pūhui peptide. Ka taea te whakamahi hei kaihoko micellar, hei roopu tiaki ranei hei tiaki i te roopu waikawa amino hei aukati i nga tauhohenga taha e kore e hiahiatia i roto i te tauhohenga matū, i te wa ano ka taea te whakapai ake i te hua. I tua atu, ka taea hoki te whakamahi mo te whakahiato o nga raau taero polypeptide me nga ngota ngota koiora e pa ana.

Ko te tikanga mo te whakarite Boc-L-Glutamic waikawa 1-benzyl ester ko te whakauru i te roopu whakamarumaru Boc ki te roopu amino o te waikawa glutamic, me te kawe i te tauhohenga esterification me te haukawa benzyl anhydride i tenei tuunga. Ko te tauhohenga ka mahia i raro i nga tikanga koretake, i nga tikanga taketake ranei, me te nuinga o te waa e tika ana kia oti te tauhohenga. Ko te hua ka taea te pure ma te whakatioatanga me etahi atu taahiraa purenga.

Mo nga korero haumaru, ko te haumaru motuhake o te Boc-L-Glutamic acid 1-benzyl ester e hiahia ana ki te rangahau me te arotake. Heoi, i te mea he matū matū, tera pea he riri me te paitini. Me whai i nga tikanga taiwhanga e tika ana i te wa e pa ana, e whakamahi ana ranei, me whai waahi haumaru tika, tae atu ki te mau taputapu whakamarumaru whaiaro (hei tauira, nga karapu taiwhanga, mohiti taiwhanga, me etahi atu). I te wa e whakamahia ana, e tuku ana ranei, me tika te tuku para kia kore ai e poke te taiao.