![Ethyl 1-(4-methoxyphenyl)-6-(4-aminophenyl)-7-oxo-4 5 6 7-tetrahydro-1H-pyrazolo[3 4-c]pyridine-3-carboxylate（CAS# 503615-07-4 ) Atahanga Whakaatu](https://cdn.globalso.com/xinchem/Ethyl14methoxyphenyl64aminophenyl7oxo4567tetrahydro1Hpyrazolo34cpyridine3carboxylate.png)
Ethyl 1-(4-methoxyphenyl)-6-(4-aminophenyl)-7-oxo-4 5 6 7-tetrahydro-1H-pyrazolo[3 4-c]pyridine-3-carboxylate（CAS# 503615-07-4 )
Kupu Whakataki
E whai ake nei he kupu whakataki mo nga rawa, nga whakamahinga, nga tikanga whakarite me nga korero haumaru o te apixaban intermediate 3:
Kounga:
Ko te Apixaban intermediate 3 he puhui waro. He totoka me te whakarewa i roto i nga whakarewa pararopi penei i te ether me te ethyl acetate.
Nga Whakamahinga: Ka whakamahia nuitia mo te mate whakamohoatanga me te maimoatanga o te mamae nui.
Tikanga:
Ko te tikanga whakarite o te apixaban intermediate 3 ka taea te whakahaere i nga waahanga e whai ake nei: Ko te waikawa p-nitrobenzoic te urupare ki te hypobutylthiourea i te noho tahi o te waikawa acetic me te thionyl chloride ki te whiwhi N-(p-nitrophenyl) -N-(hypobutylthioylurea) waikawa formic, katahi ka tauhohe ki te konutai waiwai i roto i te konutai waikura me te wairewa methanol kia whiwhi apixaban takawaenga 3.
Mōhiohio Haumaru: Me whai i nga tikanga whakahaere haumaru ina whakamahi me te whakahaere i tenei puhui. Ko te whakapanga tika, te whakangohanga ranei ka pa he kino ki te hauora o te tangata. Ko ona korero haumaru motuhake me arotake me te tukatuka i runga i nga ture me nga aratohu e tika ana kia pai ai te whakamahi me te whakahaere. I te wa e mahi ana i nga whakamatautau whakahiato matū, me whakahaere i raro i nga tikanga taiwhanga e tika ana, me whakamahi nga taputapu whakamarumaru whaiaro penei i nga karaehe matū, nga karapu whakamarumaru, me nga kakahu whakamarumaru.
