Ethyl 3-(2-((4-cyanophenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate（CAS# 211915-84-3 )

Kupu Whakataki

N-[[2-[[(4-cyanobenzenyl)amine]methyl]-1methyl-1H-5-benzimidazole]carbonyl]3-aminobenzoyl]N-2-pyridyl-b-alanine ethyl ester, whakapotohia hei N-PCBMITPAAE. E whai ake nei he kupu whakataki mo tona ahuatanga, te whakamahinga, te whakarite me nga korero haumaru:

Kounga:

Te ahua: he karaehe totoka, he karaihe kowhai marama ranei.

Wairewa: N-PCBMITPAAE he wairewa i etahi whakarewa waro, penei i te dimethyl sulfoxide me te dichloromethane. Kare e rewa i te wai.

Whakamahia:

Ko te N-PCBMITPAAE e whakamahia nuitia ana i roto i te rangahau waihanga i roto i te mara matū. He hanganga ngota uaua me nga roopu kaha, ka taea te whakamahi hei reagent, whakakorikori, hei taapiri taapiri ranei i roto i te whakahiato waro.

Tikanga:

Ko te tikanga whakarite o te N-PCBMITPAAE he uaua, me te nuinga o te waa e hiahia ana he tauhohenga maha-taahiraa. Ko te tikanga whakarite noa ko nga waahanga e whai ake nei: te whakahiatotanga o te 4-cyanoaniline me te 1-methyl-1H-5-benzimidazole, katahi ka tauhohe ki te waikawa carboatelic ki te hanga N-[(4-cyanobenzene)methyl]-1-methyl-1H- 5-benzimidazole-2-carboxylate. I muri mai, ka tauhohe ki te 3-aminobenzoyl chloride ki te hanga N-[(4-cyanobenzene)methyl]-1-methyl-1H-5-benzimidazole-2-carboxylic acid 3-aminobenzoyl ester. Ko te hua whakamutunga, ko N-PCBMITPAAE, ka hangaia e te tauhohenga me te 2-pyridyl-β-alanine ethyl ester.

Mōhiohio Haumaru:

Ko te hanganga o te N-PCBMITPAAE he uaua ake, me te tupato i te wa e whakamahia ana me te mahi. Me whai i nga tikanga taiwhanga e tika ana, me mahi nga mahi tupato, penei i te mau karapu whakamarumaru, maru kanohi, me nga kaakahu whakamarumaru. Me noho mawehe atu i nga puna whakawera me nga mea whakahaora kaha, me te pupuri i nga tikanga pai o te hau. I te wa e rongoa ana me te whakahaere i te matū matū, me whakahaere tika kia kore ai e aituā.