fmoc-O-tert-butyl-D-tyrosine (CAS# 118488-18-9)

Ko te Fmoc-O-tert-butyl-D-tyrosine he waikawa amino parea e whakamahia ana. Ko nga korero e whai ake nei mo tona ahuatanga, te whakamahinga, te hanga me nga korero haumaru:

Taiao:
Ko te Fmoc-O-tert-butyl-D-tyrosine he totoka karaihe ma. He pūhui pararopi me te tātai matū C30H31NO7 me te taumaha rāpoi 521.57g/mol. Ko te puhui he huanga o te tyrosine kei roto i te roopu amino he roopu tiaki Fmoc (9-fluorofluorenylformyl) me te roopu waikawa carboxylic ka whakahiatohia ki te O-tert-butyl.

Whakamahia:
Ko te Fmoc-O-tert-butyl-D-tyrosine e whakamahia ana hei waikawa amino parea i roto i te whakahiato peptide. Ma te whakapiri i te roopu tiaki Fmoc ki te roopu amino, ka taea te aukati i nga tauhohenga taha e kore e hiahiatia i te wa o te whakahiato. Kei te whakamahia nuitia i roto i te whakahiato wahanga totoka ka taea te whakamahi ki te whakahiato polypeptides me nga pūmua.

Tikanga Whakaritenga:
Ko te whakaritenga o te Fmoc-O-tert-butyl-D-tyrosine i te nuinga o te waa ka mahia ma te whakahiato matū. Tuatahi, ka tauhohehia te tyrosine ki te Fmoc-Cl (9-fluorofluorenylcarbonyl chloride) hei whakaputa i te Fmoc-O-tyrosine. Kātahi ka tāpirihia te Cesium tert-butyl bromide ki te tauhohenga hei whakamaarama i te roopu waikawa carboxylic hei hanga Fmoc-O-tert-butyl-D-tyrosine. I te mutunga, ka whiwhi te hua parakore i nga hikoinga o te whakamaarama, te horoi me te whakamaroke.

Mōhiohio Haumaru:
Ko te Fmoc-O-tert-butyl-D-tyrosine he pūhui pūmau i raro i ngā tikanga noa, ā, karekau e kitea te whitiwhiti i te pāmahana rūma. I te wa e whakamahia ana, me whai ki nga tikanga haumaru taiwhanga, mau taputapu whakamarumaru tika, me te karo i te pa ki te kiri me nga kanohi. I te wa e whakahaere ana, e rongoa ana ranei, me pupuri ki tetahi wahi maroke, hauhautanga, kia matara atu i te ahi me te waiora. I te wa ano, me karohia te whakapiri ki nga waikura kaha me nga waikawa kaha hei aukati i nga tauhohenga kino. Rapua he awhina hauora ina horomia, he tupono noa ranei ki te puhui.