N-Cbz-L-Leucine（CAS# 2018-66-8)
Morearea me te Haumaru
| Nga Tohu Whakamate | Xn – He kino |
| Waehere Morearea | R10 – He mura ahi R20/22 – He kino ma te horomia me te horomia. R37/38 – He whakapataritari ki te punaha manawa me te kiri. R40 – Nga taunakitanga iti o te paanga mate pukupuku R41 – He kino kino ki nga kanohi R36/37/38 – He whakapataritari ki nga kanohi, te punaha manawa me te kiri. R20/21/22 – He kino ma te horomia, ka pa ki te kiri me te horomia. R67 – Ko te kohu ka puta te momoe me te mangere R63 – He kino pea ki te tamaiti kare i whanau R19 – Ka hangaia he peroxide pahū |
| Whakaahuatanga Haumaru | S16 – Kia matara atu i nga puna o te mura. S26 – Mena ka pa ki nga kanohi, horoi tonu ki te nui o te wai me te rapu tohutohu hauora. S36/37/39 – Mau kakahu whakamarumaru tika, karapu me te whakamarumaru kanohi/kanohi. S45 – Ki te puta he aitua, ki te kore ranei koe e pai, rapu wawe i nga tohutohu hauora (whakaatuhia te tapanga ina taea.) S36 – Mau kakahu whakamarumaru tika. S36/37 – Mau kakahu whakamarumaru me nga karapu tika. S60 – Ko tenei rawa me tona ipu me tuku hei para morearea. |
| UN ID | UN 1993 3/PG 3 |
| WGK Tiamana | 3 |
| RTECS | OH2921000 |
| Waehere HS | 29242990 |
N-Cbz-L-Leucine（CAS# 2018-66-8) whakataki
Ko te Cbz-L-leucine, te ingoa katoa o Boc-L-leucine (ko Boc te tu mo te roopu tiaki dibutoxycarbonyl), he waikawa amino. E whai ake nei he kupu whakataki mo tona ahuatanga, te whakamahinga, nga tikanga whakangao me nga korero haumaru:
Kounga:
- Te ahua: Ma te kirikiriata ma
- Wairewa: Wairewa ki te waiwaro, dimethylformamide (DMF) me te dichloromethane
Whakamahia:
- Ko te CBZ-L-Leucine he roopu tiaki waikawa amino e tiaki ana i te roopu hydroxyl o te leucine i te wa o te whakahiatotanga o nga peptides kia kore ai e tauhohe ki etahi atu tauhohenga. I roto i te whakahiato peptide me whakauru nga toenga leucine maha, ka taea te whakamahi Cbz-L-leucine ki te tiaki i te roopu hydroxyl o te leucine mo nga tukanga whakahiato o muri.
- Ko te Leucine he waikawa amino nui e whai waahi nui ana ki te hanganga me te mahi o te pūmua.
Tikanga:
- Ko te whakaritenga o te Cbz-L-leucine ka whiwhihia ma te tauhohenga o te leucine me te Boc-OSu (Boc—N-nitrocarbonyl-L-leucine). I roto i te tauhohenga, ka mahi a Boc-OSu hei kaiwhakataki i te roopu whakamarumaru ka uru ki te tauhohenga esterification me te leucine hei whakaputa Cbz-L-leucine.
Mōhiohio Haumaru:
- He matū te Cbz-L-leucine, ā, me penapena pai kia matara atu i te mura me te hāora.
- I te wa e whakamahia ana, karohia te hoha i tana puehu, ka pa atu ranei ki te kiri me nga kanohi.
- Whaia nga tikanga haumaru e tika ana i te wa e whakahaere ana me te penapena, ka mau i nga taputapu whakamarumaru whaiaro penei i nga karapu taiwhanga me te whakamarumaru kanohi.
