N-Cbz-L-Threonine（CAS# 19728-63-3)

Āhuatanga matū:

Tātai rāpoi	C12H15NO5
Molar Mass	253.25
Kiato	1.2499 (whakatau tata)
Te Whakarewa	101-103°C(marama)
Piro Pouri	396.45°C (whakatau tata)
Hurihuri motuhake(α)	-4.7 º (c=4, waikawa acetic)
Tohu Kohiko	261.3°C
Wairewa	tata te marama i roto i te Methanol
Kohu Kohu	3.7E-11mmHg i te 25°C
Te ahua	Ma ki te marama kowhai te paura tioata
Tae	Mā ki Tata mā
BRN	2335409
pKa	3.58±0.10(I Matapaetia)
Tikanga Rokiroki	Kua hiri ki te maroke, Rokiroki i roto i te pouaka tio, i raro i te -20°C
Taurangi Refactive	-4.9 ° (C=2, AcOH)
MDL	MCD00065948
Whakamahi	Ka whakamahia mo nga reagents biochemical, peptide synthesis.

Tukuna he imeera ki a matou

Taipitopito Hua

Tohu Hua

Morearea me te Haumaru

Nga Tohu Whakamate	Xn – He kino
Waehere Morearea	R20/21/22 – He kino ma te horomia, ka pa ki te kiri me te horomia. R36/37/38 – He whakapataritari ki nga kanohi, te punaha manawa me te kiri.
Whakaahuatanga Haumaru	S22 – Kaua e pupuhi puehu. S24/25 – A ape i te pa ki te kiri me nga kanohi. S36 – Mau kakahu whakamarumaru tika. S26 – Mena ka pa ki nga kanohi, horoi tonu ki te nui o te wai me te rapu tohutohu hauora.
WGK Tiamana	3
Waehere HS	29242990

N-Cbz-L-Threonine（CAS# 19728-63-3) Nga korero

whakarite

tāpirihia te 50mL o L-Thr(30mmol) ka whakamataohia te otinga Na2CO3 kukū ki roto i te pounamu tauhohenga 250mL, ka whakakorikoria, ka rewa i roto i te pati hukapapa. Makahia te 20mL o te wairewa acetone Z-OSu(39.4mmol) ki roto i te pounamu tauhohenga; Whakakorikoria te tauhohenga i te 25 ℃, TLC-UV fluorescence me te tikanga tae ninhydrin te aroturuki i te tukanga tauhohenga. I muri i te tauhohenga, tāpirihia te H2O20mL, te tango me te Et2O(30mL × 2) i te pH>9, kohia te wahanga wai, te whakatika i te pH ki te 3~4 me te 1.5NHCl, te tango ki te EtOAc(30mL × 3), whakakotahi i te wahanga waro, horoi ki te wairewa NaCl kukū (25mL × 2), whakamaroke ki te Na2SO4 anhydrous, tirohia te parakore ma te TLC-ultraviolet fluorescence me te tikanga whanaketanga tae ninhydrin, me te whakaeto i raro i te pehanga iti, whakamaroke korehau ki te whiwhi i te wai kowhai kowhai N-benzyloxycarbonyl-L-threonine, kei te rongoa i te iti o te pāmahana.

Whakamahi

Ko CBZ-L-threonine te ahua tiaki N-Cbz o L-threonine (T405500). Ko te L-threonine he waikawa amino tino nui, ka whakamahia hei kai me te taapiri kai. Ko te riaka mutant o Escherichia coli i whakaputa te nui o te L-threonine mo te rangahau me te kai kai. Ko te L-threonine ka kitea i roto i nga ika me nga heihei, ka whakauruhia ki etahi o nga pūmua nui o te tinana, penei i te hemoglobin me te insulin.
Ka whakamahia mo nga reagents biochemical me te whakahiato peptide.

Tōmua: AC-TYR-NH2（CAS# 1948-71-6)

Panuku: 2-Amino-4-bromobenzoic acid（CAS# 20776-50-5)

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