Te konutai nitroprusside dihydrate (CAS # 13755-38-9)
Morearea me te Haumaru
| Waehere Morearea | R25 – He paitini ki te horomia R26/27/28 – Tino paitini ma te horomia, ka pa ki te kiri me te horomia. |
| Whakaahuatanga Haumaru | S45 – Ki te puta he aitua, ki te kore ranei koe e pai, rapu wawe i nga tohutohu hauora (whakaatuhia te tapanga ina taea.) S36/37/39 – Mau kakahu whakamarumaru tika, karapu me te whakamarumaru kanohi/kanohi. S22 – Kaua e pupuhi puehu. |
| UN ID | UN 3288 6.1/PG 3 |
| WGK Tiamana | 3 |
| RTECS | LJ8925000 |
| FLUKA BRAND F CODES | 3 |
| TSCA | Ae |
| Waehere HS | 28372000 |
| Te akomanga morearea | 6.1 |
| Roopu Tarapi | III |
| Te paitini | LD50 ā-waha i roto i te Rapeti: 99 mg/kg |
13755-38-9 - Tohutoro
| Tohutoro Whakaaturia mai ano | 1. Tian, Ya-qin, et al. “Te whakatauritenga o nga tikanga tangohanga rereke me te arotautanga o te tangohanga awhina ngaruiti… |
13755-38-9 - Kupu Whakataki
Wairewa ki te wai, paku wairewa ki te waipiro. Ko tana wairewa wai he pahekeheke, ka taea te pirau me te huri kakariki.
13755-38-9 - Nga Korero Tohutoro
| whakataki | konutai nitroprusside (taiao rāpoi: Na2[Fe(CN)5NO]· 2H2O, ingoa matū: konutai nitroferricyanide dihydrate) he vasodilator tere me te mahi poto, e whakamahia ana hei haumanu mo te whakaheke toto ohorere penei i te mate pukupuku, te mate pukupuku mate pukupuku, takawhita kino, takawhita paroxysmal i mua me muri i te pokanga pheochromocytoma, aha atu, ka taea hoki te whakamahi mo te whakahaere hypotension i te wa e mahi ana i te mate. |
| pānga | Ko te konutai nitroprusside he vasodilator tere tere, he kaha te whakamaaramatanga ki runga i nga uaua maeneene o te toto me te uaua, me te whakaiti i te aukati vascular peripheral ma te whakaheke i nga oko toto. Ka taea ano e te whakaheke toto te whakaheke i te kawenga i mua me muri i te ngakau, te whakapai ake i te putanga o te ngakau, me te whakaheke i te whakaheke toto i te wa e kore e kati te paera, kia taea ai te whakakore i nga tohu o te ngoikore o te ngakau. |
| tohu | 1. ka whakamahia mo te whakaheke ohorere o nga mate ohorere, penei i te mate whakaheke toto, te encephalopathy hypertensive, te takawhita kino, te takawhita paroxysmal i mua i muri i muri i te pokanga pheochromocytoma, ka taea hoki te whakamahi mo te whakaheke toto i te wa e mahi ana te mate. 2. Mo te ngoikore o te ngakau, tae atu ki te edema pulmonary. Ka whakamahia ano hoki mo te ngoikore o te ngakau i roto i te mate o te myocardial infarction, i te kore ranei e kati te piha (mitral, aortic valve) ranei. |
| pharmacokinetics | ka eke ki te taumata o te toto i muri tonu i te maturuturunga o te toto, ka whakawhirinaki tona taumata ki te horopeta. Ko tenei hua ka whakahekehia e nga toto toto whero ki roto i te cyanide, ko te cyanide i roto i te ate ka whakawhitia ki te thiocyanate, kaore he mahi vasodilating te metabolite; Ka taea hoki e te cyanide te uru atu ki te kaitao o te huaora B12. Ko tenei hua ka mahi tata tonu i muri i te whakahaerenga, ka tae ki te taumata o te mahi, ka mau tonu mo te 1~10 meneti i muri i te whakamutua o te whakaheke toto. Ko te haurua o te ora o nga turoro me te mahi renal noa he 7 ra (i inehia e te thiocyanate), ka roa te wa e ngoikore ana te mahi renal, he iti rawa ranei te konutai toto, ka peia e te whatukuhu. |
| He tukanga waihanga mo te whakarite | te konutai nitroprusside, tae atu ki nga waahanga e whai ake nei: 1) Te whakahiato i te parahi nitroso ferrocyanide: te taapiri i te nui o te wai purea hei tareka i te nitroso-ferricyanide pāhare pāporo i roto i te tank whakatioatanga, whakamahana ki te 70-80 ℃ kia memeha katoa, me te āta tāpiri i te konukura sulfate pentahidrate. wairewa wairewa dropwise, i muri i te tauhohenga te pupuri mahana mo te 30 meneti, centrifuge, te Ko te keke tātari centrifuged (copper nitroso ferricyanide) i kuhua ki roto i te tank crystallization. 2) Te konutai nitroprusside (konutai nitronitroferricyanide): Whakapaia he wairewa wai konutai konutai kukū i runga i te ōwehenga kai, ka āta taka ki roto i te nitroso ferricyanide i te 30–60 nekehanga C. I muri i te tauhohenga, centrifuge, kohia te filtrate me te wai. 3) Te kukū me te whātioatanga: Ko te filtrate me te wai ka kohia ka maminga ki te tank kukū korehau, ka āta tāpirihia te waikawa acetic glacial kia kore noa e puta he mirumiru. Tahurihia te papu korehau me te wera ake ki te 40-60 nga nekehanga C, timata te kukū, te aro ki te maha o nga tioata rerenga, kati te paera mamaoa, te hiko hiko ki te whakarite mo te whakamaaramatanga. 4) Te whakamaroke Centrifugal: i muri i te whakamaroketanga, ka tangohia te supernatant, ka oho me te centrifuged nga tioata, ka whakanohoia te keke tātari ki roto i te pereti kowiri tira, ka whiwhi te hua ma te whakamaroke korehau. |
| mahi koiora | Ko te Sodium Nitroprusside he vasodilator kaha e mahi ana ma te tuku noa i te NO i roto i te toto. |
| Whainga | Uara |
| Whakamahi | Ka whakamahia hei reagent mo te whakatau i nga aldehydes, ketones, sulfides, zinc, sulfur dioxide, etc. Ka whakamahia hei reagent mo te whakatau i te aldehydes, acetone, sulfur dioxide, zinc, Alkali metals, sulfide, etc. Ko nga Vasodilators. Manatokonga o te aldehydes me te ketones, zinc, sulfur dioxide and alkali metal sulfide. Te tātari chromatic, te whakamatautau mimi. |
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